Human African Trypanosomiasis (Sleeping Sickness)

Human African Trypanosomiasis (Sleeping Sickness)

Human African Trypanosomiasis (HAT), also known as sleeping sickness, is a vector-borne parasitic disease caused by infection with the Trypanosoma parasite that is transmitted to humans through the bites of infected tsetse flies.


An estimated 70 million people in 36 countries in sub-Saharan Africa are currently at risk of HAT. Continued control efforts have resulted in drecreases in the number of reported cases; the estimated number of actual cases is currently 30,000. 


Sleeping sickness occurs only in sub-Saharan Africa and many of the affected populations live in remote areas with limited access to health services, which hampers the surveillance, diagnosis and treatment of cases.


Early stage symptoms of sleeping sickness include fever, swollen lymph glands, aching muscles and joints, headaches and irritability. In advanced stages, the disease attacks the central nervous system, causing changes in personality, alteration of the biological clock, confusion, slurred speech, seizures and difficulty in walking and talking; if not treated, the person will die.



TDR, the Special Programme for Research and Training in Tropical Diseases. African trypanosomiasis.



Control of sleeping sickness is based on reduction of the reservoirs of infection by early diaagnosis and control of tsetse flies.



TDR, the Special Programme for Research and Training in Tropical Diseases. African trypanosomiasis.



Read more at ZeroFly® Livestock

Recent News

  • Malaria No More honors Mikkel Vestergaard as one of ten innovators that will make possible the end of malaria in our lifetimes
  • US President’s Malaria Initiative visits Vestergaard-Noguchi Memorial Institute for Medical Research
  • Vestergaard joins Roll Back Malaria and Business Alliance against Malaria at World Health Assembly calling for the rapid uptake of innovative tools to eliminate malaria

Malaria Research

IR Mapper is a tool that helps inform vector control strategies by mapping insecticide resistance in mosquitoes that transmit malaria, Zika, Dengue and other mosquito borne diseases. This helps inform vector control strategies.


Buy LifeStraw®

For consumer purchases, visit LifeStraw® to find a local retailer. For each consumer purchase, one school child in Africa will receive clean water for an entire school year. For large quantities purchased for public health settings, contact us


Contact Us

Connect with us

Subscribe to e-newsletter

facebook new  twitter new  linkedin new  youtubesquare 

Our Partners

  • carter
  • malarianomore
  • rollback
  • unitednations
  • worldvision